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(Senior) Research Associate, Cell Biology/in vivo Pharmacology

October 18th 2024

To help drive the development of its neurovascular/CNS-focused product pipeline, Neuvasq is looking for a (Senior) Research Associate, Cell Biology/in vivo Pharmacology.

Mission Description

  • Your responsibilities:Support the development of cell-based assays or in vitro platforms that recapitulate various aspects of the biology of the blood-brain or blood-retinal barriers.
  • Design, express and purify engineered proteins for downstream evaluation.
  • Evaluate molecules for their ability to interfere with pathways involved in the blood-brain or blood-retinal barriers homeostasis.
  • Contribute to in vivo studies aiming at the evaluation of selected molecules in relevant neurovascular disease models.
  • Report to Senior Scientists and Head of Drug Discovery or Preclinical Development.

 

Candidate profile

Skills & Expertise:

  • Good knowledge of general molecular biology and cloning techniques, including vector construction.
  • Practical experience in cell culture techniques, including ideally primary cells culture.
  • Experience in vectors design and recombinant protein expression in eukaryotic systems.
  • Hands-on experience in protein purification techniques such as affinity chromatography, IEX, HIC and SEC.
  • Knowledge of general protein chemistry techniques, such as SDS-PAGE, western-blot, or ELISA. Experience with FACS would be an additional asset.
  • Demonstrated experience in handling, injecting and dissecting mice (and rats).
  • Demonstrated experience with tissue sectioning, histology, and/or Immunohistochemistry.
  • Experience with microscopy and image analysis is a plus.
  • Previous experience with in vivo animal studies of CNS biology is a plus.
  • French speaking environment but a good knowledge of English is recommended.
  • Well organized, flexible, and rigorous.
  • Team-spirit oriented.
  • Ability and willingness to learn.

Minimum Qualifications:

  • A BSc or MSc degree in biochemistry, biomedical engineering, molecular biology, chemistry, life science or similar fields.
  • FELASA B certificate or higher
  • Considerable previous experience in a similar position is required.

 

Offer

What is in for you:

  • A full-time contract in an exciting start-up environment.
  • Close collaboration with a team of experts.
  • A unique opportunity for personal development.
  • A competitive salary according to experience.

 

Contact Details

If interested, please send your resume and cover letter to the following address: info@neuvasq.com, mentioning the reference JOB-2024-CELL BIOLOGY & IN VIVO PHARMACOLOGY in the e-mail object. Your application and related information will remain strictly confidential.