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Senior Scientist Immunology

March 13th 2022

The mission of Ncardia Belgium is to understand human iPSC and developmental biology, and harness this knowledge to develop and manufacture iPSC therapeutics that significantly improve patient outcomes. We are convinced that pluripotent stem cell technology is the key to get better, more efficient treatments to patients faster. To achieve this mission, we are building a world-leading research facility to overcome the complexicty and challenges of iPSC lineage specification. We will know we have succeeded when we can reliably and rapidly generate cell products that consistently produce positive outcomes in patients. We are an enthusiastic, skilled, and committed international team in which everyone has the opportunity to make a decisive contribution. For more information about the company, please visit our website at www.ncardia.com. Within our Cell Therapy Innovations (CTI) team in Gosselies (Belgium) there is one position immediately available: Senior Scientist Immunology, iPSC Cell Therapy R&D. The selected candidate will report to the Director, Cell Therapy Innovations.

Mission Description

The position
As a Senior Scientist in Immunology, focusing oniPSC Cell Therapy R&D, your key responsibilities will be to develop new hiPSC differentiation processes and associated analytical methods to lead to the generation of hiPSC-based immunotherapies. You have a strong background in immunology or developmental immunology. You are self-motivated with a strong focus on innovation, and critical thinking, and with experience in a service organization or demonstratable soft skills that are needed for commercial projects.
  
Responsibilities
  • Lead and deliver R&D studies focused upon the generation of novel hiPSC-derived immune cell types according to defined timelines, budget and milestones. Customer sponsored projects are part of the position
  • Manage the testing of new approaches and generate high quality analytical readouts to develop, optimize and characterize hiPSC differentiation processes and/or final immune cell products
  • Coordinate work with laboratory technicians, and assistant/associate scientists
  • Provide scientific background and feedback on results to the assistant/associate scientist(s) assigned to his/her studies
  • Ensure accurate internal data reporting including protocols, technical and scientific reports
  • Generate scientific proposals to resolve key technical hurdles associated with his/her studies
  • Initiate and generate ideas based on scientific readings and research, and therefore contribute to research plans and company IP
  • Be up to date with scientific literature and maintain knowledge concerning relevant new research and new technologies within Ncardia’s scientific field
  • Represent the CTI group internally and collaborate with project teams (e.g., business development, QA, communication, strategy, project management)
  • Contribute to or lead scientific presentations (customer update of sponsored projects, peer-reviewed publications, white papers, conference presentation) and collaboration with external stakeholders
  • Draft and review Standard Operating Procedures (SOPs)
  • Participate in technology transfer of processes to the Manufacturing group
As part of the job responsibility includes hands-on processes development, the preferred candidate is a motivated researcher with desire to work in a laboratory including occasional cell maintenance during the weekend

Candidate profile

Qualifications
  • Ph.D. or Post-doc in developmental immunology or cell biology, immunology, or other relevant discipline. 
  • Strong scientific and technical background evidenced by high quality peer-reviewed publication record, successful funding applications and / or evidence of collaborative studies aligned with the level of experience of the candidate.
  • Experience with flow cytometry, qPCR and functional immunological assays (e.g., cytokine release assay, flow cytometry, cytotoxicity, and proliferation assays). 
  • Familiarity with generation and interpretation of large datasets.
  • Attention for detail, and drive for problem solving.
  • Excellent organization, project and time management skills.  Timelines may be demanding. 
  • Capacity to innovate and contribute to company IP.
Additional experience of value: 
  • Expertise in stem cell biology with experience in expansion and differentiation of hiPSCs
  • Familiarity with QbD/DoE approaches
  • Knowledge of regulatory requirements for Good Manufacturing Practices (cGMP)

Since we are working in an international environment; proficiency in English, both written and spoken, is a prerequisite, working knowledge of French would be an advantage.

As a person, you are benevolent, open-minded and a good communicator. You have a high level of energy that drives you and inspires others.

You are a true team-player who enjoys working in close collaboration with colleagues in and out of the laboratory.

You can work in demanding and dynamic work environment and understand that this position requires flexibility.

You have a problem-solving attitude, take initiatives, and think outside the box. 

Offer

We offer you a challenging position in a dynamic biotech company with room for personal growth and development.  We provide a competitive salary package based on your education and experience.

Contact Details

Interested?
Send your motivation letter with curriculum vitae to Elodie Noël at careers@ncardia.com